PK/PD & Exposure–Response Modeling: From Concentrations to Decisions that Hold Up in Review
PK/PD & Exposure–Response Modeling: From Concentrations to Decisions that Hold Up in Review Model-Informed Evidence: Turning PK/PD and Exposure–Response into Defensible Clinical Decisions Why Exposure–Response Matters: Connecting Concentration, Effect, and Regulatory Decisions Pharmacokinetics/pharmacodynamics (PK/PD) and exposure–response (E–R) analyses translate what the body does to the drug—and what the drug does to the body—into dose, regimen,…