Statistical Analysis Plans & DMC Charters: Estimand-Aligned Analyses, Interim Boundaries, and Audit-Ready Governance
Statistical Analysis Plans & DMC Charters: Estimand-Aligned Analyses, Interim Boundaries, and Audit-Ready Governance Authoring SAPs and DMC Charters That Keep Science, Safety, and Compliance in Sync Why SAPs and DMC Charters matter—and how to architect them together In modern clinical development, two documents quietly determine how results will be believed and how patients will be…