Multiplicity & Subgroup Analyses: Controlling Error and Interpreting Heterogeneity in Clinical Trials
Multiplicity & Subgroup Analyses: Controlling Error and Interpreting Heterogeneity in Clinical Trials Making Confident Claims: Error Control and Subgroup Evaluation That Stand Up to Review Why Multiplicity Matters and How Subgroup Questions Fit the Big Picture Multiplicity arises whenever a trial makes more than one statistical claim—multiple endpoints (primary and key secondary), multiple time points,…